Orlando Pownall QC is cited as a leader in crime by The Legal 500, and also as a "Star" Silk by Chambers UK, in which he is described as "a good cross-examiner, a silky smooth clever brief who defends well and has a huge presence in court". He is widely regarded as one of the leading jury advocates of his generation. Since taking Silk in 2001, he has defended almost exclusively, and has been involved in a variety of high profile cases including the representation of Danny Preddie, who was charged with murder of Damilola Taylor, and Sean Hoey, who was alleged to have been responsible for the Omagh bombing and other bombings in Northern Ireland. He also defended the man charged with the murder of Robert McCartney. He has also defended in prosecutions brought under the Medicines Act and was instructed in the trial of allegations relating to so called ‘Cartel' activity by pharmaceutical companies. In the last year he has appeared before the Supreme Court and Judicial Committee of the Privy Council in two significant criminal appeals. This year he is instructed in a number of high profile murders including an historical allegation of rape and murder and a double murder in Braintree. He is also instructed in a number of regulatory matters including forfeiture proceedings under the Proceeds of Crime Act and prosecutions brought by the MHRA, together with proceedings under the Trade Descriptions Act. He also specialises in Appeals. Orlando is also cited by the industry guides as a leader in Fraud and Financial Crime, and he regularly represents professionals who face white collar proceedings. He is instructed to defend in Operation Tabernula (2014) the FCA's largest ever market abuse prosecution. He was appointed Head of Chambers at 2 Hare Court in October 2009.